Web21 de out. de 2016 · Doses of simvastatin >10 mg/d and doses of lovastatin >20 mg/d when used with diltiazem or verapamil are not recommended. However, it should be noted that verapamil labeling recommends a higher dose limit of lovastatin of 40 mg/d when coadministered with verapamil. Web4 de mar. de 2024 · We searched for published articles that compared the lipid-lowering effects and safeties of high-intensity statin (daily dose lowers LDL cholesterol on average by ≥ 50%) and low/moderate-intensity statin (daily dose lowers LDL cholesterol on average by < 50%) plus ezetimibe.
Cardio protective drugs: Statins & more - European Society of …
WebTable 5. Statin Dose Intensity and Equivalency Chart* Statin Intensity %LDL-C Reduction HMG-CoA Reductase Inhibitor Rosuvastatin Atorvastatin Pitavastatin Simvastatin … Web15 de jul. de 2024 · We compared the effectiveness of low‐ or moderate‐intensity (LMI) versus high‐intensity (HI) statin dose on clinical outcomes in patients with peripheral artery disease. Methods and Results We reviewed patients with symptomatic peripheral artery disease who underwent peripheral angiography and/or endovascular intervention … rbm tree service
Cholesterol Management Guide for Health Care Practitioners
Web21 de out. de 2024 · A moderate-intensity statin is recommended. And for those with multiple risk factors, consideration should be given to high-intensity statin to reduce LDL-C by ≥50%. In persons with ASCVD, the LDL-C should be reduced by ≥50% with the highest tolerated dose of high-intensity statin. If LDL remains >70 mg/dl, it is reasonable to … Web23 de ago. de 2024 · High-intensity statin regimens comprised atorvastatin at 80 mg (8 studies), atorvastatin at 40 mg (5 studies), rosuvastatin at 20 mg (1 study), and simvastatin at 80 mg (2 studies). Mean patient age ranged between 56.5 and 75.2 years. Follow-up was performed for 12 months, on average (range, 1–60 months). Risk of methodological bias WebHigh-intensity statins lower LDL-C by at least 50 percent on average while moderate-intensity statins lower LDL-C by approximately 30-49% on average. The table below outlines the specific statins and doses for low-, moderate-, and high-intensity statin therapy. Statin hydrophilicity. rbm to php