WebPhosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell … WebPhospho-YAP1 (Ser397) Antibody (PA5-110163) in WB Western blot analysis of Phospho-YAP1 (Ser397) in NIH/3T3, NIH/3T3 (treated with Forskolin). Samples were incubated in polyclonal Phospho-YAP1 (Ser397) antibody ( Product # PA5-110163) using a dilution of 1:1000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10000. Product Details
Phospho-YAP1 (Ser127) Polyclonal Antibody - Thermo …
WebJul 9, 2024 · Knockdown of FAT1/2 resulted in Hippo pathway inactivation, as judged by a marked decrease in the levels of phospho-MST1 (pMST1) and phospho-YAP1 (pYAP1) (Supplementary Fig. 3a). WebMonoclonal Anti-phospho-YAP1 (pTyr357) (mouse IgM isotype) is derived from the hybridoma PYP-76 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a synthetic phosphopeptide corresponding to a fragment containing (pTyr357) of human YAP1 conjugated to KLH. small concrete repairs near me
Anti-phospho-YAP1 (pTyr 357 ) antibody produced in …
WebPhospho-YAP1 is retained in the cytoplasm. In the absence of Hippo signaling, YAP1 translocates to the nucleus, associates with co-activators TEAD1-4, and functions as a transcriptional factor promoting the expression of key target genes. Components of the Hippo pathway are mutated in human cancers, and deregulation of this pathway plays a … WebJul 23, 2024 · The gene that has received the most attention in the literature is YAP1, which was found to be involved in the development and progression of CRC [ 5, 6, 9, 10 ]. The gene was reported to be overexpressed in 52.5% (73/139) of CRC, and the YAP1 protein was predominantly localized to the nucleus [ 11 ]. WebDot Blot: Transcriptional coactivator YAP1 (phospho Y357) peptide General notes This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free production small condo decor with glam